Tag: Cancer Genetics

BRCA Testing for Breast Cancer Awareness Month

Breast Cancer

Goal of Breast Cancer Awareness Month – Get BRCA Tested if you have a Family History of Breast or Ovarian Cancer

 

Breast cancer is the most common cancer in women, affecting one in eight women in their lifetime for a background population risk of 12.5%. In the US, last year, the national Cancer Institute estimated 231,840 new cases of female breast cancer. The majority of breast cancers are sporadic meaning there is not an inherited component. However 5 to 10% are due to inherited causes.

Although BRCA1 and BRCA2 were the first genes identified to be associated with this inherited risk for cancer they are only responsible for about 50% of hereditary breast cancer. However, additional genes have been discovered that are associated with increased breast cancer and ovarian cancer risk and with these other genes there is often other cancers such as pancreatic cancer, thyroid cancer or sarcoma in the family.

Genetic Cancer Risk

Indications for breast cancer testing

  • Early-onset breast cancer
  • Having a male relative with breast cancer
  • Having a history of breast and ovarian cancer in the same individual or in closely related family members
  • Multiple members of a family with breast cancer
  • Multiple members of the family with breast, uterine or thyroid cancer

Benefits of testing

Early detection improves the odds of survival

 

cancer survival

 

 

 

 

In addition, identifying and inherited susceptibility for certain cancers can change both screening and management of your health

  • Earlier acceptance of screening tools such as mammograms, ultrasound and MRI
  • Indication for risk reducing measures such as ovary removal after childbearing is complete
  • Identify other at risk family members
  • Consideration for medications for primary risk reduction

Expanded BRCA Test Panel – Now Available for Breast Cancer Awareness Month

Test description – our advanced BRCA panel includes BRCA1, BRCA2, CDH1, PALB2, PTEN, TP53 and many other genes associated with the increase risk of breast and ovarian cancer. In fact the current panel consists of 30 genes and represents a comprehensive genetic analysis for hereditary cancers including breast, ovarian, colorectal, pancreatic and other cancers as well.
Testing is performed in a CLIA certified laboratory with strong performance standards showing 100% accuracy, 100% sensitivity, 100% specificity with both repeatability and reproducibility

This Expanded BRCA Panel can be ordered on our Facebook page

 

 

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